| Bioactivity | Dopamine D3 receptor ligand-2 (compound 8) is a potent D3 receptor ligand with a Ki of 11.4 nM. Dopamine D3 receptor ligand-2 have high selectivity for D3 over D2 (Ki=1228 nM). Dopamine D3 receptor ligand-2 has the potential for Cocaine use disorder (CUD) research[1]. |
| Name | Dopamine D3 receptor ligand-2 |
| Formula | C27H29N5O |
| Molar Mass | 439.55 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Benjamin E. Blass, et al. Synthesis of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides and their evaluation as D3 receptor ligands. Medicinal Chemistry Research volume 31, pages735–748 (2022). |
Dopamine D3 receptor ligand-2
CAS: F: C27H29N5O W: 439.55
Dopamine D3 receptor ligand-2 (compound 8) is a potent D3 receptor ligand with a Ki of 11.4 nM. Dopamine D3 receptor l
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